High Protein Chicken Parmesan Casserole – Easy and Delicious Dinner

High Protein Chicken Parmesan Casserole is the kind of dish that makes busy weeknights feel a little cozier and a lot tastier. Imagine all the comfort of classic Chicken Parmesan—but easier, cheesier, and packed with lean protein to keep you full and satisfied. If you’re juggling work, family, and the never-ending “what’s for dinner?” question, this recipe is about to be your new best friend.

It’s simple, uses everyday ingredients, and still tastes like something you’d get from your favorite Italian spot. Whether you’re feeding a hungry crew or meal-prepping for the week, this casserole hits that perfect balance of healthy and indulgent. And yes, it’s totally freezer-friendly—because who doesn’t love having a homemade dinner ready to go?

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What is High Protein Chicken Parmesan Casserole?

High Protein Chicken Parmesan Casserole takes the beloved flavors of Chicken Parmesan—crispy breadcrumbs, tangy marinara, melty cheese—and transforms them into a hearty, family-style bake. Instead of frying chicken breasts, this recipe uses shredded cooked chicken, which saves time and keeps the dish lighter.

The ricotta and mozzarella add creaminess, the Parmesan gives that classic sharp kick, and the whole wheat breadcrumbs bring a satisfying crunch on top. It’s like a cozy Italian hug in casserole form, but with a high-protein twist that fits perfectly into a balanced lifestyle. Whether you’re following a high-protein meal plan or just want a filling, guilt-free dinner, this casserole is the answer.

Reasons to Try High Protein Chicken Parmesan Casserole

There are plenty of reasons this High Protein Chicken Parmesan Casserole deserves a permanent spot in your weekly rotation. First, it’s quick—prep it in just 15 minutes. Second, it’s incredibly versatile. You can use rotisserie chicken, leftover grilled chicken, or even turkey. Third, it’s protein-packed, meaning you’ll stay fuller longer (no post-dinner snack raids!). It’s also family-approved—kids love the cheesy layers, and adults love that it’s actually good for them.

Plus, it’s freezer-friendly, which makes it perfect for meal prepping or those nights when cooking feels impossible. Pair it with a green salad or some roasted veggies, and dinner’s done. For another quick and healthy chicken dish, check out Easy Chicken Fajita Rice Casserole—another reader favorite for busy nights.

Ingredients Needed to Make High Protein Chicken Parmesan Casserole

• 2 cups cooked and shredded chicken
• 1 cup marinara sauce
• 1 cup ricotta cheese
• 1 cup shredded mozzarella cheese
• ½ cup grated Parmesan cheese
• 1 teaspoon dried basil
• 1 teaspoon dried oregano
• Salt and pepper to taste
• 1 cup whole wheat breadcrumbs

Instructions to Make High Protein Chicken Parmesan Casserole – Step by Step

Let’s roll up our sleeves and make this High Protein Chicken Parmesan Casserole together, step by step. Don’t worry—this isn’t one of those overly complicated recipes that leave your kitchen looking like a crime scene. We’re keeping things simple, delicious, and weeknight-friendly.

Step 1: Preheat Your Oven and Prepare the Dish

First things first, preheat your oven to 375°F (190°C). This temperature gives you the perfect balance—hot enough to melt the cheese into creamy perfection, but not so high that it burns the breadcrumbs before the inside gets bubbly. While the oven heats up, grab a 9×13-inch casserole dish and give it a quick spritz of nonstick cooking spray or a light brush of olive oil. This little step keeps cleanup easy later (and prevents that tragic moment when the cheese sticks to the pan).

If you’re new to casseroles or love make-ahead dinners, check out my Easy Chicken Fajita Rice Casserole—it uses the same oven-baked layering technique and is another lifesaver on hectic nights.

Step 2: Mix the Base — The Heart of the Casserole

In a large mixing bowl, combine 2 cups of shredded chicken, 1 cup of marinara sauce, 1 cup of ricotta cheese, 1 teaspoon each of dried basil and oregano, and a sprinkle of salt and pepper. This is the soul of your casserole—creamy, herby, and savory all in one go. Mix everything gently with a large spoon until the chicken is evenly coated. The mixture should look rich and slightly pink from the sauce, with specks of green herbs peeking through.

If you like a touch of spice, feel free to add a pinch of crushed red pepper flakes or a dash of garlic powder. For an extra flavor punch, try using a homemade or quality store-bought marinara—your casserole will thank you. For a flavor variation, you might love my High Protein Honey Garlic Butter Chicken, which offers another protein-rich, saucy favorite that pairs perfectly with Italian-style meals.

Step 3: Layer the Ingredients — Step by Step for Even Flavor

Now it’s time to assemble the layers—arguably the most satisfying part. Spread half of your chicken mixture evenly across the bottom of the casserole dish. This first layer lays the foundation for that gooey, cheesy magic that’s about to happen.

Next, sprinkle half of your mozzarella cheese (½ cup) and Parmesan cheese (¼ cup) evenly over the top. Cheese placement matters—it ensures each bite is perfectly balanced with melty, creamy goodness.

Repeat this process with the remaining chicken mixture, then finish with the remaining mozzarella and Parmesan. Think of it like creating an edible lasagna without all the noodles. Every layer you add builds flavor, texture, and richness.

Want to sneak in more nutrients? Toss in a handful of spinach or some sautéed mushrooms between the layers. (Picky eaters rarely notice, trust me.) You can find more hidden-veggie dinner ideas in my Healthy Italian Penicillin Soup article—it’s another clever way to pack in goodness without sacrificing comfort.

Step 4: Add the Crunch — Breadcrumb Topping Time

This step is all about texture. Sprinkle your 1 cup of whole wheat breadcrumbs evenly over the top of the casserole. The breadcrumbs give it that golden, crispy finish reminiscent of traditional Chicken Parmesan but with a lighter, whole-grain twist.

If you’re feeling fancy (or just love a good crunch), lightly drizzle or spray olive oil on top. This helps the breadcrumbs toast up beautifully while baking. You can even mix a tablespoon of melted butter into the breadcrumbs beforehand for an extra-rich topping.

For a quick guide on mastering golden, crispy toppings, you might want to check out my Easy Garlic Parmesan Chicken and Potatoes—it uses a similar breadcrumb-and-cheese topping that comes out irresistible every time.

Step 5: Bake — Step by Step to Golden Perfection

Place your casserole in the preheated oven and bake for 25–30 minutes. You’ll know it’s ready when the cheese is bubbling, the sauce is peeking through the sides, and the top has turned that dreamy golden-brown shade. The smell? Pure Italian comfort.

If your oven runs hot, check it at the 25-minute mark to make sure the top doesn’t overbrown. If it needs a little more color, switch on the broiler for the last minute or two—but keep a close eye, or you’ll go from “crispy” to “oops” real fast.

While it bakes, you can whip up a quick side like a simple green salad or some garlic-roasted vegetables. If you’re craving something lighter but equally satisfying, try my Grilled Chicken and Broccoli Bowls—a perfect pairing for this high-protein meal prep theme.

Step 6: Rest, Serve, and Enjoy

Once it’s done baking, take the casserole out and let it rest for at least 5 minutes. This helps the cheesy layers set slightly, making it easier to slice and serve cleanly. Then, dig in! Each bite should have that comforting blend of creamy ricotta, savory chicken, tangy marinara, and crispy breadcrumbs.

You can serve this with a fresh Caesar salad, roasted zucchini, or even garlic bread if you’re going full Italian tonight. The leftovers taste incredible the next day (honestly, maybe even better).

If you’re planning to make this ahead or freeze it for later, check out the storage tips in my High Protein Chicken Orzo post—another meal-prep superstar with easy freezer-friendly instructions.

Step 7: Optional Add-Ons and Customizations

If you want to get creative, this step-by-step recipe leaves plenty of room for personalization. You can:

• Add a layer of sautéed spinach or roasted vegetables for extra fiber.
• Swap the marinara for a spicy arrabbiata sauce for more kick.
• Use cottage cheese instead of ricotta for a lighter texture and even more protein.
• Sprinkle a little crushed red pepper or Italian seasoning on top for extra flair.

This High Protein Chicken Parmesan Casserole step by step guide proves that you don’t need fancy techniques or hours in the kitchen to make something comforting, nutritious, and family-approved.

What to Serve with High Protein Chicken Parmesan Casserole

This casserole pairs beautifully with a fresh Caesar salad, roasted broccoli, or even garlic green beans. For something carb-friendly, try serving it with zucchini noodles or cauliflower rice. If you’re craving something heartier, whole-grain pasta or a slice of crusty sourdough does the trick. And if you love balanced, high-protein dinners, don’t miss Grilled Chicken and Broccoli Bowls for a lighter yet equally satisfying option.

Key Tips for Making High Protein Chicken Parmesan Casserole

• Use rotisserie chicken to save time. It’s flavorful and perfect for casseroles.
• Don’t skip the resting time after baking—it helps the casserole hold its shape.
• Add a handful of spinach or kale for extra nutrients.
• Want extra crunch? Mix a tablespoon of melted butter into the breadcrumbs before topping.
• To make it lower in fat, use part-skim ricotta and mozzarella.

Storage and Reheating Tips for High Protein Chicken Parmesan Casserole

Store leftovers in an airtight container in the fridge for up to 4 days. To reheat, cover with foil and bake at 350°F for about 15 minutes or microwave in 1-minute bursts until hot. For long-term storage, freeze individual portions for up to 3 months. To reheat from frozen, thaw overnight in the fridge, then bake until heated through. It tastes just as delicious the next day—maybe even better!

FAQs

Can I use cottage cheese instead of ricotta? Absolutely! Cottage cheese works perfectly for a lighter texture and extra protein.
Can I add vegetables? Yes! Spinach, zucchini, or mushrooms blend right in without overpowering the flavor.
Is this recipe gluten-free? It can be! Just swap the whole wheat breadcrumbs for gluten-free ones.
Can I make it ahead? Definitely. Assemble it the night before, refrigerate, and bake fresh the next day.

Final Thoughts

High Protein Chicken Parmesan Casserole isn’t just another dinner—it’s comfort made smarter. With simple ingredients, plenty of protein, and loads of flavor, it’s the kind of recipe that makes healthy eating feel easy. Whether you’re cooking for your family or meal prepping for yourself, this casserole checks every box: quick, hearty, and downright delicious. For another cozy high-protein dinner idea, visit High Protein Chicken Orzo—a creamy, satisfying dish that complements this casserole beautifully.

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